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Anadrol 50 (Oxymetholone)

Contents: 1. Anadrol description 2. Anadrol Characteristics 3. Stacking and Use 4. How and where buy Anadrol online

Anadrol description Drug Class: Highly Anabolic/Androgenic Steroid (Oral)

Pharmaceutical Name: Oxymetholone

Brand Name: Anadrol

Effective Dose: 50-150 mg / day orally

Active Life: Less than 16 hours

Acne: Yes

Water Retention: Yes, high

High Blood Pressure: Yes

Liver Toxic: Yes, very high

Aromatization: Debatable

DHT Conversion: It is a derivative of DHT

Decrease HPTA function: Yes, extreme

How To Use Anadrol: Anadrol is unfortunately also the most harmful oral steroid. Its intake can cause many considerable side effects. Since it is I 7-alpha alkylated it is very liver toxic. Most users can expect certain pathological changes in their liver values after approximately one week. An increase in liver values of both the enzymes GOT and GPT also called transaminases, often cannot be avoided. Elevated GOT and GPT values are indications of hepatitis, i.e. a liver infection. Longer intake and/or higher doses can cause a yellow discoloration of fingernails, eyes, or skin jaundice). This is because oxymetholone induces an increase of biliburin in the liver, producing a bile pigment which causes the yellow discoloring of the skin. The liver enzyme gamma-GT also reacts sensitively to the oxymetholone, causing it to elevate

Anadrol Dosage: As for the dosage, opinions differ. A dosage sufficient for any athlete would be 0,5 – 0,8 mg per pound of body weight/day. This corresponds to 1-4 tablets; i.e. 50-200 mg/day. Under no circumstances should an athlete take more than four tablets in any given day. We are of the opinion that a daily intake of three tablets should not be exceeded. Those of you who would like to try Anadrol for the first time should begin with an intake of only one 50 mg tablet. After a few days or even better, after one week, the daily dosage can be increased to two tablets, one tablet each in the morning and evening, taken with meals. Athletes who are more advanced or weigh more than 220 pounds can increase the dosage to 150 mg/day in the third week.Athletes continue their treatment with injectable testosterone such as Sustanon or Testosterone enanthate for several weeks. Bodybuilders often combine Anadrol with Deca-Durabolin or Testosterone to build up strength and mass. Anadrol is to be taken seriously and the prevailing bodybuilder mentality “more is better” is out of place.

Anadrol characteristics

Anadrol (Oxymetholone) is without a doubt the strongest and most visibly active steroid to date. Not only does it act very rapidly, it causes a virtual explosion of mass. Gains of up to 10 pounds in 2 weeks are not uncommon. This is largely due to a moderate to low androgenic effect combined with a high anabolic activity also mediated by non-AR mechanisms (mechanisms other than simply binding the androgen receptor). You can imagine that the gains made on Anadrol aren’t the leanest. You would note a drastic smoothing out of the muscle due to estrogen-related fat (lipolysis) and water retention. This lipolysis has been shown to be rather drastic. One study1 on long-term hemodialysis patients showed beyond a doubt the role that Anadrol can play in causing hyperlipedemia. The fat deposition rate, post-hepatic (after processing by the liver), increased drastically in the Anadrol group while numbers remained stable in the control group.

It has been suggested that the estrogenic effects of Anadrol (Oxymetholone) may not be as much mediated by estrogen, as by Anadrol itself activating the estrogen receptor. Because there is little to no aromatisation off Anadrol, the possible progestational effect was examined first. Similar to that of nandrolone perhaps. But a study2 testing the progestational effects of Anadrol and methandrostenolone against those of testosterone as well as nandrolone and its metabolites showed that the progestagenic activity of Anadrol wasn’t even in the neighbourhood of that of testosterone, let alone nandrolone. Ruling out the possibility of progestagenic activity and aromatisation, that only left Anadrol engaging in a structure with the estrogen receptor itself. Since it has an A-ring similar to that of estradiol (the prime estrogen) so this would be the most logical explanation. Since progesterone acts as an estrogen agonist, it would require circulating estrogen to negotiate such levels of water build-up as Anadrol causes, so it seemed like a far-fetched idea to begin with.

The water component resulting from Anadrol (Oxymetholone) use is not be under-estimated either. The benefit of water retention is of course a lubrication of the joints, allowing the comfort of pain-free workouts even with extremely heavy weights, as well as the retention of more nutrients inside the cell, possibly leading to more permanent growth in muscle tissue. The downside to a massive water retention is that it gives you a rather puffed up look. A look not uncommon in off-season competitive bodybuilders and the heaviest classes of powerlifters. With the estrogen increase of course comes the increased risk of more side-effects such as gynocomastia (growth of breast tissue in men). Therefore its always advised that a cycle of Anadrol is accompanied by the use of an anti-estrogen such as Nolvadex. Nolvadex, keeping in mind that aromatase enzyme is not involved, would be the wiser choice as it blocks the receptor for estrogen rather than the aromatase enzyme. Its wise to note as well that the gains from Anadrol are largely mediated by estrogen, so reducing estrogen may reduce results as well.

Because it is mild androgen as well as a potent estrogen, blood volume is increased. Androgens raise the red blood cells (although this has been shown to happen through a mechanism other than erythropoesis3) to improve aerobic performance while estrogens increase the white blood cells in an attempt to stimulate the immunity. Couple that increase in blood cells to an increase in water and you get a serious increase in blood volume. This effect has been known to result in magnificent pumps for the users of Anadrol products. The synthesis of extra erythrocytes (Red blood cells) also increases stamina and performance (this effect is largely negated by the larger estrogenic component. Anadrol (Oxymetholone) is not a good product for athletes). Together with the unbelievable strength effect of Anadrol’s water retention that makes for some incredible workouts. On a side note, these characteristics make for anadrol’s popular use in treating anemia.

The Use Of Anadrol: The use of Anadrol (Oxymetholone) should be strict and brief. While it is no doubt the strongest steroid, quantitatively, its also by far the most hazardous steroid to your health. Apart from the great risk of common steroid-related side-effects (acne vulgaris, benign prostate hypertrophy, gynocomastia and androgenetic alopecia), it also has numerous other side-effects. Most notable is Anadrol’s hepatoxicity (damaging to the liver) : Its standard 17-alpha-alkylated as with most oral steroids, resulting in an inavoidable raise in liver transaminase enzyme counts. The most frequent of the hepatoxic effects is jaundice4 (yellow coloration of the skin) due to an Anadrol induced increase in biliburine, but others include peliosis hepatis and formation of hepatic tumors (cancer). And that’s not all. There is also a number of intrinsic side-effects noted with the use of this steroid. Headaches, stomach aches, nausea, vomiting, insomnia and diarrhea are among common afflictions associated with Anadrol use.

A lot of Oxymetholone products were discontinued in the early 90’s due to the high rate of side-effects, making them rather uninteresting. The renewed interest came when it was being effectively used in the treatment of the wasting disease AIDS, sparking a comeback. Nonetheless users should note that the original 50 mg Anadrol50 was taken over by Unimed. The original Anadrol50 by Syntex is no longer made or found. There has also been a surge of legit underground compounds such as the Ttokkyo oxymetolona 50. So be careful and do your homework when looking for Anadrol.

Stacking and Use: Anadrol is an oral only compound and is 17-alpha alkylated with a methylgroup to allow for a higher yield when having to traverse the liver, as with most oral compounds. As such it has a good degree of hepatoxicity and should not be used for longer than 6 weeks on end and it is highly recommended that you get your liver values checked regularly. Because of its long activity and poor affinity (due the the 17AA) good results can be obtained with a single daily dose, so spreading your doses out is an option but is anything but necessary. A single dose of 50-100 mg every day is recommended, but doses as high as 150 or 200 are used by experienced bodybuilders as well. Due to its rapid action and high toxicity, its mostly used to kickstart a longer injectable cycle in the first 3-5 weeks of that cycle. It will add a lot of mass and strength on immediately, getting you through the low-result beginning of an injectable cycle. Its use is thus very similar to that of Dianabol, but with the latter being slightly more versatile.

As such it makes a good match early in a stack with you standard testosterone/nandrolone stacks, with boldenone (equipoise) and methenolone (primobolan) as well. Since it has a high intrinsic affinity for the estrogen receptor and next to no intrinsic affinity for the androgen receptor I doubt anyone would contemplate using this for cutting. To even out the massive water retention one might choose to stack it with trenbolone (finaplix/parabolan) or stanazolol (Winstrol/Stromba) but never for the purpose of looking lean. Anadrol, like Dianabol, may also be one of the few orals that has real merit when using it alone. Although the gains are often hard, near impossible to keep afterwards.

In terms of secondary drugs, I wish I had a lot to recommend here, but really there isn’t much to be helped with Anadrol. Even with liver protection it would still do serious damage and with every bit of added protection, the efficacy rate of Anadrol would go down. As for estrogen maintenance, Nolvadex being the strongest of estrogen receptor antagonists comes highly recommended and preferably in higher than normal doses, 30-40 mg, as its Anadrol itself that is the culprit and not its aromatized form. On the other hand, we need to take into account that more than half of Anadrol’s anabolic action stems from this estrogenic action as well. So its sort of trading less side-effects for gains. One thing that is advised is blood pressure medication as extreme hypertension has been noted. And I’ll say it a third and last time, its best to get regular liver check-ups when taking Anadrol.

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Learn more about Anadrol (Oxymetholone)

Mark Henry
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